Join us on June 7, 2011 for our FREE Membrane Protein Crystallography Webinar presented by Prof. Michael C. Wiener, Ph.D. Use less protein and accelerate the process of crystallizing Membrane Proteins using the Patent Pending Memb-PASS Screening Kits from Omscientia.
Prof. Wiener, and members of his laboratory at the University of Virginia, have developed, and licensed to Omscientia, a microplate-based detergent screening method that rapidly characterizes the stability and size of membrane proteins exchanged into a large panel of ninety-four different detergents. The entire assay utilizes sub-milligram quantities of membrane protein, and requires only several hours to perform. Additionally, the Wiener lab has developed, and licensed to Omscientia, a matched set of pre-crystallization solubility and crystallization screens. Once the protein is in a suitable detergent, as determined by the (differential filtration) assay, a twenty-four-condition solubility screen is used to determine the proper protein concentration for crystallization. Once at proper concentration, the protein can then be set up for crystallization with an innovative ninety-six-condition screen, developed and tuned for integral membrane protein crystallization.