The ZT First Pass Fragment Screening Libraries contain 352 compounds and have been optimized to cover as much diversity space as possible and are pre-grouped into shape-diverse mixtures for crystallographic screens.  These compounds are carefully selected from more than 10 million compounds.  Potencies for compounds with these properties typically range from 1-10,000 uM. Highly soluble (200mM in 100% DMSO), the library is suitable for screening with NMR, SPR and x-ray crystallography.  There are 352 compounds in total.

• A number of in-house computational approaches including psuedo-3D pharmacophore mapping, Bayesian probability modeling and bio-property prediction schemes are used during our selection process.
   
• Compounds may be screened by common methods such as x-ray crystallography, NMR, or SPR. Since the fragments are selected for solubility, they may also be appropriate for high-concentration biochemical screens and have been used successfully for protein families such as kinases.
   
• Compounds arrive pre-plated with 96 Compounds in Corning 3363 V-bottom plates and Plugged Seal with Corning 3080 Seals.
   
• For instructions and recommendations on use of the Fragment Screens please click here.
   
• Huge Academic Discounts are available.  Please contact Omscientia at info@omscientia.com to obtain your Discount Code good for one full year for valid Academic labs ordering this product.